Rank the stack by mechanism, not hype.

TCM: Blocks the mouth-nose gate before pestilential qi can enter the Lung boundary.

Modern: Source and exposure reduction is the highest-confidence intervention for inhaled infectious or aerosolized risk.

Caution: Fit matters. Facial hair, poor seal, reuse, and moisture undermine protection.

Prevention and exposure reduction only; does not treat infection after symptoms appear.

TCM: Do not stir the pestilential field. Remove the exposure before asking the body to compensate.

Modern: Hantavirus prevention depends on avoiding aerosolized rodent urine, droppings, and nesting material.

Caution: Follow public-health cleanup guidance. Do not dry sweep or vacuum rodent-contaminated spaces.

Exposure prevention only.

TCM: Acts at the nose and mouth gate, matching Wu Youke's entry-path logic for pestilential qi.

Modern: Seaweed-derived sulfated polysaccharide with respiratory-virus RCTs and published synergy with Griffithsin in SARS-CoV entry models.

Caution: Use only as directed by the product label. Not proven for hantavirus treatment.

Consumer mucosal support with respiratory-virus evidence; no Andes-virus treatment claim.

TCM: Modern environmental medicine: clear the room so the Lung does not have to fight the room.

Modern: Reduces airborne particles when sized correctly for room volume and used continuously.

Caution: Does not replace respirators, ventilation, rodent remediation, or medical care.

Environmental risk reduction; not a clinical intervention for HPS.

TCM: Strengthens the exterior before invasion; must stop when fever or active infection declares.

Modern: Immunomodulatory prevention logic, not acute infection management.

Caution: Critical warning: stop at fever onset or suspected active infection unless a qualified practitioner directs otherwise.

Prevention-phase exterior support only; contraindication logic is central.

TCM: Supports Lung, Heart, and Kidney terrain without the same exterior-consolidating warning as Huang Qi.

Modern: Immune modulation, inflammation balancing, and respiratory resilience logic.

Caution: May interact with anticoagulants or immune-suppressive therapy. Use clinician judgment.

Terrain support; not a substitute for antivirals, respiratory monitoring, or emergency care.

TCM: Tonifies the Lung-Kidney axis: breath, endurance, constitutional reserve, and recovery depth.

Modern: Cordycepin, adenosine-adjacent signaling, fatigue physiology, and immune-modulation literature.

Caution: Review anticoagulants, autoimmune disease, pregnancy, and immune-modifying medications.

Supportive terrain logic; no direct Andes-virus clinical-efficacy claim.

TCM: Supports righteous qi as a baseline terrain correction, especially when deficiency is likely.

Modern: Vitamin D status influences innate immune signaling, antimicrobial peptides, and respiratory infection risk.

Caution: Consider testing, hypercalcemia risk, kidney disease, sarcoidosis, and clinician guidance at high doses.

Nutrient sufficiency support; not a treatment for HPS.

TCM: Fits the clear-heat, stabilize-inflammation lane without being a classical herb.

Modern: Studied for viral entry, ionophore-adjacent zinc logic, mast-cell modulation, and inflammatory control.

Caution: Medication interactions are possible. Use caution with kidney disease and anticoagulant contexts.

Mechanistic adjunct only; not a replacement for physician evaluation.

TCM: Supports Metal terrain: Lung and Large Intestine boundary integrity.

Modern: Antiviral cofactor, epithelial barrier support, and immune-cell function relevance.

Caution: Avoid chronic high-dose zinc without copper monitoring. Review nausea and medication timing.

Nutrient support, not disease treatment.

TCM: Supports the Lung terrain and phlegm-fluid transformation side of the protocol.

Modern: Glutathione precursor, mucolytic, redox support, and possible viral surface protein interference.

Caution: Can affect bleeding risk and interact with nitroglycerin. Clinician guidance for acute disease.

Respiratory and redox support; not a hantavirus therapy.

TCM: Supports tissue resilience and heat-damage buffering, but is not a viral-entry gate blocker.

Modern: Fat-soluble carotenoid antioxidant with lipid membrane and inflammatory relevance.

Caution: Take with food. Not a Griffithsin analog beyond broad marine-origin association.

Antioxidant terrain support. The Institute scores it far below iota-carrageenan as a Griffithsin-adjacent analog.

TCM: Supports fluids and tissue integrity when heat threatens to consume the body's reserves.

Modern: Antioxidant recycling, immune-cell function, collagen and endothelial support logic.

Caution: High doses can cause diarrhea and may be inappropriate in some kidney stone or iron-overload contexts.

Supportive nutrient; no Andes-virus treatment claim.

TCM: A modern way to support inflammatory resolution before heat runs out of control.

Modern: Specialized pro-resolving mediator precursor logic and immune-membrane composition support.

Caution: Review anticoagulants, surgery, fish allergy, and GI tolerance.

Baseline inflammation-resolution support; not acute HPS management.

TCM: Clears heat toxin and is historically central in Chinese epidemic response.

Modern: Broad antiviral literature across enveloped respiratory viruses; best framed as exposure/early-stage support.

Caution: Discuss dosing and constitution with a qualified practitioner, especially with pregnancy, medications, or active illness.

Traditional and mechanistic rationale only; not established as hantavirus treatment.

TCM: A Kidney-Water and antioxidant terrain support in modern language, relevant when heat consumes fluids.

Modern: Selenoproteins support redox balance and immune function; deficiency can worsen viral outcomes.

Caution: Narrow therapeutic window. Avoid stacking multiple selenium products.

Correcting deficiency and redox support only.

TCM: Moves blood and modulates inflammatory heat, but does not directly map to the Mo Yuan strategy.

Modern: NF-kB and inflammatory pathway literature; plausible adjunct, not protocol core.

Caution: Medication interactions, gallbladder issues, surgery, and anticoagulant concerns need clinician review.

Interesting inflammation adjunct, lower priority than the core stack.

TCM: Chuan Xin Lian is bitter cold, heat-clearing, and best suited to declared heat-toxin presentations.

Modern: Human respiratory infection evidence and anti-inflammatory signaling relevance.

Caution: Avoid in pregnancy and use care with autoimmune disease, anticoagulants, or fertility concerns.

Respiratory-infection evidence exists, but Andes-specific treatment efficacy is not established.

TCM: Potentially relevant to righteous qi signaling, but outside classical self-care territory.

Modern: Immunomodulatory peptide studied in viral illness and immune dysfunction contexts.

Caution: Prescription/research territory. Do not self-source peptides for suspected hantavirus.

Research and physician-only conversation; not a public protocol recommendation.

TCM: Clears Lung heat and damp-heat; important in formulas where heat is damaging fluids and vessels.

Modern: Baicalin, baicalein, and wogonin literature overlaps with NF-kB, IL-6, TNF-alpha, and endothelial inflammation.

Caution: Use Scutellaria baicalensis, not American skullcap. Review liver disease and drug interactions.

Mechanistic and classical rationale; active illness should be clinician-guided.

TCM: Wu Youke's formula for reaching the membrane source before pestilential qi declares.

Modern: Maps to incubation-window intervention logic rather than post-crisis suppression.

Caution: Complex formula. Do not self-assemble from loose herbs without qualified guidance.

Classical practitioner framework; no retail self-treatment recommendation.

TCM: Vents heat from the Wei boundary when fever first declares.

Modern: Early symptomatic upper-respiratory formula logic; does not address pulmonary crisis alone.

Caution: Wrong stage or constitution can make formula choice inappropriate.

Early-stage classical support, not an HPS treatment.

TCM: A tissue-repair hypothesis, not a Wen Bing antiviral strategy.

Modern: Repair and inflammatory modulation claims are not enough to place it in the active protocol.

Caution: Experimental/research territory. No public recommendation for hantavirus prevention or treatment.

Low-priority research concept; included so the database documents why it is not central.

TCM: A seaweed-derived boundary-defense concept that makes the mouth-nose gate discussion more precise.

Modern: Red-algae lectin studied for binding viral glycoproteins and blocking entry in enveloped-virus models.

Caution: Not a supplement. Do not self-source research compounds.

Research platform only; use iota-carrageenan as the practical consumer analog conversation.